WebApr 12, 2024 · Alkylphosphonates have found widespread applications in pharmaceuticals, agrochemicals, and materials science, and their synthesis is of paramount imp… WebOct 1, 2024 · A simple one-pot approach was developed for the synthesis of furan-2(5H)-one derivative containing indole fragments. This method includes the telescoped multicomponent reaction of indole, 4-methoxyphenylglyoxal, and Meldrum’s acid. The synthetic utility of the prepared furan-2(5H)-one was demonstrated by condensation with …
13.4 Phosphoranyl radicals X4P•, including related species
WebA general protocol for the hydroacylation of styrenes from aliphatic carboxylic acids is reported. These reactions proceed via β-scission of a phosphoranyl radical that is accessed by photoredox catalysis, followed by addition of the resulting acyl radical to the styrenyl olefin. We show that phosphine tunability is critical for efficient intermolecular coupling … WebThe term phosphoranyl radical strictly refers to those four-coordinate phosphorus species which have nine valence shell electrons, Z 4 P·, and seems first to have been used by … thomas fiel do
Effects of Substituents on the Stability of Phosphoranyl Radicals
WebApr 19, 2024 · A photoinduced, phosphoranyl radical-mediated protocol for the direct N-O cleavage of strained cycloketone oximes via a polar/SET crossover process was developed for the first time. This visible-light-driven direct N-O activation mode for oxime offers beneficial features such as streamlined syntheti … WebApr 12, 2024 · The rate ratio of 5- exo cyclization versus intermolecular phosphonylation (with complex B) was approximately 24:1 for hex-5-enyl radical, as illustrated in Scheme 5. The rate constant for the cyclization of hex-5-en-1-yl radical at 20°C was measured by Ingold and coworkers to be around 2.3 × 10 5 s −1. 53. WebPhosphoranyl Radicals Our lab also has an interest in exploiting phosphoranyl radical reactivity to activate strong bonds under the mild conditions conferred by photoredox … thomas fielding scott