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Consomic strain

WebJun 29, 2016 · Background: Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently … WebNov 24, 2024 · These strains allow reproducible and efficient whole-chromosome mapping (Flint and Eskin, 2012 ). In contrast, consomic strains, also termed chromosome substitution strains, possess a substitution of one whole chromosome pair from the donor strain into the genetic background of the host strain.

Special Mouse Strains Resource - The Jackson Laboratory

WebStrains Made from Multiple Inbred Strains 4.1 Recombinant Inbred Strains 4.2 Mixed Inbred Strains 4.3 Recombinant Congenic Strains 4.4 Advanced Intercross Lines 5. … http://informatics.jax.org/silver/chapters/3-3.shtml imdb dial of destiny https://lgfcomunication.com

Neonatal lethality of mouse A/J-7SM consomic strain is caused by …

WebConsomic strains are a variation on congenic strains in which a whole chromosome — rather than one local chromosomal region — is backcrossed from a donor strain onto a recipient background. In almost all cases, the donor chromosome is the Y. Like … Inbreeding depression will not occur when a new inbred strain is begun with two … 9.2 RECOMBINANT INBRED STRAINS 9.2.1 Overview 9.2.1.1 … J:301 Snell GD, Preliminary data on crossing-over between H-2, and Fu, Ki … WebFeb 11, 2015 · Using experimental allergic encephalomyelitis (EAE), a mouse model of MS, we evaluated genetic control of disease course among a panel of 26 consomic strains of mice inheriting chromosomes from the wild-derived PWD strain on the C57BL/6J background, which models the genetic diversity seen in human populations. WebBackground Chromosome substitution strains (CSSs, also referred to as consomic strains or lines) have been developed as a tool to identify chromosomes harboring quantitative trait loci (QTLs) for complex phenotypes, such as behav- ioral traits. list of lwa

Congenic Strain - an overview ScienceDirect Topics

Category:Neonatal lethality of mouse A/J-7SM consomic strain is caused …

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Consomic strain

Special Mouse Strains Resource - The Jackson Laboratory

http://www.informatics.jax.org/mgihome/nomen/strains.shtml WebA chromosome substitution strain (CSS) or consomic strain is an inbred strain in which a single chromosome from a donor strain replaces the corresponding chromosome in …

Consomic strain

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WebAn inbred strain that contains a single entire chromosome from another strain. Consomic (or Chromosome Substitution Strains) are derived by backcrossing to a parental inbred … WebConsomic strains are special type of congenic strains. The differential segment between the consomic strain and its parental (progenitor) strain is represented by a whole chromosome. Consomic strains are often used …

WebMar 1, 2003 · Like the consomic strains, these congenic strains also represent a renewable resource. The use of congenic strains has been very limited until this time because development of a congenic line typically requires 10–12 generations of backcrossing, after completion of the crossbreeding studies to define the QTL of interest. ... WebNov 1, 2010 · called a consomic strain in which part or an entire chromosome is moved from one inbred. strain to another. An example is the C57BL/6J-Chr11.3 PWD/Ph /ForeJ created by Dr. Jiri.

WebFeb 27, 2024 · To assess the role of ChrY genetic variation on susceptibility to IAV infection, we studied male mice from a panel of 11 B6-ChrY consomic strains of mice using mouse-adapted Puerto Rico A/PR/8/34 H1N1 (PR8) IAV by challenging them with 5 × 10 3 egg infectious units (EIU), equivalent to ∼1 B6-LD 50.A significant overall effect of strain on … WebApr 8, 2015 · The consomic strains have been derived from C57BL/6J (host strain) and A/J (donor strain) inbred lines. The work contributes to the value of the mouse as an animal model for studying the genetic background of differences in baseline circulating total and HDL cholesterol levels. The consomic strain survey suggested that mouse …

WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. …

WebTwo consomic mouse strains (C3H-Chr 11 NSY and C3H-Chr 14 NSY ) were previously established using the speed congenic method [5]. Congenic lines were produced as previously described [28] by... list of lymph node diseasesWebConsomic strains Consomic inbred strains are also created through successive backcrossing to a different inbred strain, but the choice of breeders is based on an entire … imdb diary of a teenage girlWebany consomic strain within 6 months, by an F2 intercross of the consomic with the background parental strain. These rats are likely to become a national resource for rat research. The website, which currently gets 2,000 visits per month (figure 3), enables investigators to download data or to use the analytical imdb die another day 200WebFeb 11, 2016 · Of the 23 genes within the narrowed congenic interval, 12 were differentially expressed between the resistance vasculature of the 2 … imdb diary of a wimpy kid long haulWebJun 29, 2016 · Chromosome substitution strains (CSSs, also referred to as consomic strains or lines) have been developed as a tool to identify chromosomes harboring … imdb dirty linesWebApr 1, 2008 · Genomes of consomic mouse strains. Centromeres are shown at the top. (Green) MSM/Ms-derived chromosomes; (blue) B6 chromosomes. The genetic background and mitochondria DNA were confirmed to be ... imdb different worldWebNov 1, 2015 · This creates the consomic strain that shares with its host strain the same 1) genetic background (including chrY PAR, autosomes, chrX, mitochondrial DNA) and 2) pre- and postnatal maternal environment (including inoculated microbiota). list of luzon provinces and its capital